- CD31/PECAM-1 (Endothelial Cell Marker) Antibody
- MyBioSource.com
- Pricing InfoSupplier PageView Company Product Page
- MBS4381159
- 0.5 mL
- Monoclonal
- Human, Monkey, Rabbit
- Antibody Purified from Bioreactor Concentrate by Protein A/G and conjugated to various reporter molecules. Prepared in 10mM PBS with 0.05% BSA and 0.05% azide. Contact us if you require this Ab in a different format
- Flow Cytometry (FC/FACS), Immunofluorescence (IF)
- Mouse
- ~100kDa (endothelium) and ~130kDa (platelets)
- CD31/PECAM-1
- Purified Ab conjugated to CF488
- platelet and endothelial cell adhesion molecule 1
- CD31/EndoCAM, PECAM-1, CD31, PECA1, GPIIA', endoCAM
- Unconjugated
- IgG1 kappa
- C31.7
Specifications/Features
CD31 (PECAM-1) is a transmembrane glycoprotein member of the immunoglobulin supergene family of adhesion molecules. CD31 is expressed by stem cells of the hematopoietic system and is primarily used to identify and concentrate these cells for experimental studies as well as for bone marrow transplantation. Anti-CD31 has shown to be highly specific and sensitive for vascular endothelial cells. Staining of nonvascular tumors (excluding hematopoietic neoplasms) is rare. CD31 MAb reacts with normal, benign, and malignant endothelial cells which make up blood vessel lining. The level of CD31 expression can help to determine the degree of tumor angiogenesis, and a high level of CD31 expression may imply a rapidly growing tumor and potentially a predictor of tumor recurrence